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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
36.67
Human Site:
T425
Identified Species:
53.78
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
T425
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Chimpanzee
Pan troglodytes
P60051
493
55922
T425
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
G393
Q
A
V
L
T
H
Q
G
R
S
S
S
S
G
H
Dog
Lupus familis
XP_537306
545
61461
T476
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
T424
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Rat
Rattus norvegicus
NP_001008302
493
55958
T424
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
R366
A
V
L
T
H
Q
G
R
S
S
S
S
G
H
Y
Chicken
Gallus gallus
XP_419150
492
55612
T423
Y
D
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Frog
Xenopus laevis
Q6GNI6
523
60030
T422
K
L
R
R
K
I
T
T
Y
V
S
F
P
L
E
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
P434
M
N
G
Q
Y
Q
Q
P
V
D
S
L
N
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
A409
S
G
Y
Y
T
L
Q
A
V
L
T
H
K
G
R
Honey Bee
Apis mellifera
XP_395043
497
56311
T422
Y
S
L
Q
A
V
L
T
H
R
G
R
S
S
S
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
T399
Y
D
L
K
G
I
I
T
H
K
G
R
S
S
Q
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
T436
Y
E
L
Q
A
V
L
T
H
Q
G
R
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
E404
P
Q
E
G
T
S
S
E
K
E
T
H
M
T
G
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
L420
K
K
H
F
P
P
N
L
E
K
G
E
N
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
100
6.6
6.6
N.A.
0
86.6
60
93.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
100
26.6
26.6
N.A.
6.6
93.3
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
50
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
44
0
0
0
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
7
7
0
0
0
0
7
7
7
0
7
0
0
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
7
7
7
7
0
7
7
0
0
63
0
7
13
7
% G
% His:
0
0
7
0
7
7
0
0
57
0
0
13
0
7
7
% H
% Ile:
0
0
0
0
0
13
7
0
0
0
0
0
0
0
0
% I
% Lys:
13
7
0
7
7
0
0
0
7
13
0
0
7
0
0
% K
% Leu:
0
7
63
7
0
7
50
7
0
7
0
7
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
0
0
0
0
13
7
0
% N
% Pro:
7
0
0
0
7
7
0
7
0
0
0
0
7
7
0
% P
% Gln:
7
7
0
57
0
13
19
0
0
44
0
0
0
0
7
% Q
% Arg:
0
0
7
7
0
0
0
7
7
7
0
57
0
0
7
% R
% Ser:
7
7
0
0
0
7
7
0
7
13
25
13
63
57
57
% S
% Thr:
0
0
0
7
19
0
7
63
0
0
13
0
0
7
0
% T
% Val:
0
7
7
0
0
50
0
0
13
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
57
0
7
7
7
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _